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Using Functional Genetics to Understand Breast Cancer Biology

Genetic screens were for long the prerogative of those that studied model organisms. The discovery in 2001 that gene silencing through RNA interference (RNAi) can also be brought about in mammalian cells paved the way for large scale loss-of-function genetic screens in higher organisms. In this arti...

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Detalles Bibliográficos
Main Authors: Ashworth, Alan, Bernards, Rene
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890198/
https://ncbi.nlm.nih.gov/pubmed/20519343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a003327
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