Molecular mechanisms involving sigma receptor–mediated induction of MCP-1: implication for increased monocyte transmigration

Cocaine abuse hastens the neurodegeneration often associated with advanced HIV-1 infection. The mechanisms, in part, revolve around the neuroinflammatory processes mediated by the chemokine monocyte chemotactic protein-1 (MCP-1/CCL2). Understanding factors that modulate MCP-1 and, in turn, facilitat...

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Autores principales: Yao, Honghong, Yang, Yanjing, Kim, Kee Jun, Bethel-Brown, Crystal, Gong, Nan, Funa, Keiko, Gendelman, Howard E., Su, Tsung-Ping, Wang, John Q., Buch, Shilpa
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2010
Materias:
Vascular Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890169/
https://ncbi.nlm.nih.gov/pubmed/20354174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-266221
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