Antigenic structure of human hepatitis A virus defined by analysis of escape mutants selected against murine monoclonal antibodies.
We examined the antigenic structure of human hepatitis A virus (HAV) by characterizing a series of 21 murine monoclonal-antibody-resistant neutralization escape mutants derived from the HM175 virus strain. The escape phenotype of each mutant was associated with reduced antibody binding in radioimmun...
Enregistré dans:
| Publié dans: | J Virol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
1992
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289013/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1312628/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.4.2208-2216.1992 |
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