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Expression of Dog Microdystrophin in Mouse and Dog Muscles by Gene Therapy

Duchenne muscular dystrophy (DMD) is characterized by the absence of dystrophin. Several previous studies demonstrated the feasibility of delivering microdystrophin complementary DNA (cDNA) into mouse and normal nonhuman primate muscles by ex vivo gene therapy. However, these animal models do not re...

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Detalhes bibliográficos
Main Authors: Pichavant, Christophe, Chapdelaine, Pierre, Cerri, Daniel G, Dominique, Jean-Christophe, Quenneville, Simon P, Skuk, Daniel, Kornegay, Joe N, Bizario, João CS, Xiao, Xiao, Tremblay, Jacques P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890099/
https://ncbi.nlm.nih.gov/pubmed/20179674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.23
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