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Differential cytokine regulation by NF-κB and AP-1 in Jurkat T-cells

BACKGROUND: Activator protein (AP)-1 and nuclear factor (NF)-κB largely control T-cell activation, following binding of foreign antigens to the T-cell receptor leading to cytokine secretion. Elevated levels of pro-inflammatory cytokines and chemokines such as TNF, IL-6 and CXCL8 are associated with...

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Autors principals: Khalaf, Hazem, Jass, Jana, Olsson, Per-Erik
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889865/
https://ncbi.nlm.nih.gov/pubmed/20507572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-11-26
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