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Minocycline inhibits glial proliferation in the H-Tx rat model of congenital hydrocephalus

BACKGROUND: Reactive astrocytosis and microgliosis are important features of the pathophysiology of hydrocephalus, and persistent glial "scars" that form could exacerbate neuroinflammation, impair cerebral perfusion, impede neuronal regeneration, and alter biomechanical properties. The pur...

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Detalhes bibliográficos
Main Authors: McAllister, James P, Miller, Janet M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889858/
https://ncbi.nlm.nih.gov/pubmed/20507614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8454-7-7
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