Transmembrane and Ubiquitin-Like Domain Containing 1 (Tmub1) Regulates Locomotor Activity and Wakefulness in Mice and Interacts with CAMLG

Tmub1 (C7orf21/HOPS) encodes a protein containing a ubiquitin-like domain. Tmub1 is highly expressed in the nervous system. To study its physiological function, we generated mice with Tmub1 deleted by homologous recombination. The knockout mice were grossly normal and viable. In a comprehensive beha...

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Detalhes bibliográficos
Main Authors: Zhang, Wandong, Savelieva, Katerina V., Suwanichkul, Adisak, Small, Daniel L., Kirkpatrick, Laura L., Xu, Nianhua, Lanthorn, Thomas H., Ye, Gui-Lan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889838/
https://ncbi.nlm.nih.gov/pubmed/20582322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011261
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