Efficient Generation of Germ Line Transmitting Chimeras from C57BL/6N ES Cells by Aggregation with Outbred Host Embryos

Genetically modified mouse strains derived from embryonic stem (ES) cells have become essential tools for functional genomics and biomedical research. Large scale mutagenesis projects are producing libraries of mutant C57BL/6 (B6) ES cells to enable the functional annotation of every gene of the mou...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Gertsenstein, Marina, Nutter, Lauryl M. J., Reid, Tammy, Pereira, Monica, Stanford, William L., Rossant, Janet, Nagy, Andras
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2010
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889837/
https://ncbi.nlm.nih.gov/pubmed/20582321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011260
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