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In Vitro Identification of Novel Plasminogen-Binding Receptors of the Pathogen Leptospira interrogans

BACKGROUND: Leptospirosis is a multisystem disease caused by pathogenic strains of the genus Leptospira. We have reported that Leptospira are able to bind plasminogen (PLG), to generate active plasmin in the presence of activator, and to degrade purified extracellular matrix fibronectin. METHODOLOGY...

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Bibliographic Details
Main Authors: Vieira, Monica L., Atzingen, Marina V., Oliveira, Tatiane R., Oliveira, Rosane, Andrade, Daniel M., Vasconcellos, Silvio A., Nascimento, Ana L. T. O.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889836/
https://ncbi.nlm.nih.gov/pubmed/20582320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011259
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