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Inhibition of Connective Tissue Growth Factor Overexpression in Diabetic Retinopathy by SERPINA3K via Blocking the WNT/β-Catenin Pathway

OBJECTIVE: Connective tissue growth factor (CTGF) is a major fibrogenic factor. Increased retinal CTGF levels have been implicated to play a role in diabetic retinopathy. SERPINA3K is a serine proteinase inhibitor, and its levels were decreased in retinas with diabetic retinopathy. The purpose of th...

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Detalhes bibliográficos
Main Authors: Zhang, Bin, Zhou, Kevin K., Ma, Jian-xing
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889783/
https://ncbi.nlm.nih.gov/pubmed/20299474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1056
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