Redox Modulation Protects Islets From Transplant-Related Injury

OBJECTIVE: Because of reduced antioxidant defenses, β-cells are especially vulnerable to free radical and inflammatory damage. Commonly used antirejection drugs are excellent at inhibiting the adaptive immune response; however, most are harmful to islets and do not protect well from reactive oxygen...

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Detalhes bibliográficos
Main Authors: Sklavos, Martha M., Bertera, Suzanne, Tse, Hubert M., Bottino, Rita, He, Jing, Beilke, Joshua N., Coulombe, Marilyne G., Gill, Ronald G., Crapo, James D., Trucco, Massimo, Piganelli, Jon D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
Assuntos:
Immunology and Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889773/
https://ncbi.nlm.nih.gov/pubmed/20413509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0588
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