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trans-dominant inhibition of human immunodeficiency virus type 1 Rev occurs through formation of inactive protein complexes.

The human immunodeficiency virus type 1 Rev protein controls expression of certain viral RNAs by binding to these RNAs in the nucleus. To investigate how dominant negative Rev mutants inhibit Rev function, we fused such mutants to hormone-dependent localization signals from the glucocorticoid recept...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Hope, T J, Klein, N P, Elder, M E, Parslow, T G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288971/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1548742/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.4.1849-1855.1992
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