Myocardin-related transcription factors regulate the Cdk5/Pctaire1 kinase cascade to control neurite outgrowth, neuronal migration and brain development

Numerous motile cell functions depend on signaling from the cytoskeleton to the nucleus. Myocardin-related transcription factors (MRTFs) translocate to the nucleus in response to actin polymerization and cooperate with serum response factor (Srf) to regulate the expression of genes encoding actin an...

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Bibliographic Details
Main Authors: Mokalled, Mayssa H., Johnson, Aaron, Kim, Yuri, Oh, Jiyeon, Olson, Eric N.
Format: Artigo
Language:Inglês
Published: Company of Biologists 2010
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889604/
https://ncbi.nlm.nih.gov/pubmed/20534669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.047605
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