Palmitoylation stabilizes unliganded rod opsin

S-palmitoylation is a conserved feature in many G protein–coupled receptors (GPCRs) involved in a broad array of signaling processes. The prototypical GPCR, rhodopsin, is S-palmitoylated on two adjacent C-terminal Cys residues at its cytoplasmic surface. Surprisingly, absence of palmitoylation has o...

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Bibliografske podrobnosti
Main Authors: Maeda, Akiko, Okano, Kiichiro, Park, Paul S.-H., Lem, Janis, Crouch, Rosalie K., Maeda, Tadao, Palczewski, Krzysztof
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889565/
https://ncbi.nlm.nih.gov/pubmed/20404157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000640107
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