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Experimental detection of knotted conformations in denatured proteins
Structures that contain a knot formed by the path of the polypeptide backbone represent some of the most complex topologies observed in proteins. How or why these topological knots arise remains unclear. By developing a method to experimentally trap and detect knots in nonnative polypeptide chains,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2889543/ https://ncbi.nlm.nih.gov/pubmed/20393125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912161107 |
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