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Uncoupling of growth plate maturation and bone formation in mice lacking both Schnurri-2 and Schnurri-3

Formation and remodeling of the skeleton relies on precise temporal and spatial regulation of genes expressed in cartilage and bone cells. Debilitating diseases of the skeletal system occur when mutations arise that disrupt these intricate genetic regulatory programs. Here, we report that mice beari...

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Hlavní autoři: Jones, Dallas C., Schweitzer, Michelle N., Wein, Marc, Sigrist, Kirsten, Takagi, Tsuyoshi, Ishii, Shunsuke, Glimcher, Laurie H.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889532/
https://ncbi.nlm.nih.gov/pubmed/20404140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003727107
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