Effects of mutations within the 3' orf open reading frame region of human T-cell lymphotropic virus type III (HTLV-III/LAV) on replication and cytopathogenicity.

Mutations that eliminated the ability of the human T-cell lymphotropic virus type III to produce the 27-kilodalton 3' orf product did not eliminate the ability of the virus to replicate in and kill T4+ cells. A mutant carrying a mutation that deleted carboxy-terminal sequences from the envelope...

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Bibliographic Details
Published in:J Virol
Main Authors: Terwilliger, E, Sodroski, J G, Rosen, C A, Haseltine, W A
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1986
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288951/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3490583/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.60.2.754-760.1986
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