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A Francisella novicida pdpA mutant exhibits limited intracellular replication and remains associated with the lysosomal marker LAMP-1

Several genes contained in the Francisella pathogenicity island (FPI) encode proteins needed for intracellular growth and virulence of Francisella tularensis. The pdpA gene is the first cistron in the larger of the two operons found in the FPI. In this work we studied the intracellular growth phenot...

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Detalhes bibliográficos
Main Authors: Schmerk, Crystal L., Duplantis, Barry N., Howard, Perry L., Nano, Francis E.
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889414/
https://ncbi.nlm.nih.gov/pubmed/19372155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.025445-0
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