Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon

Crohn's disease (CD), a major form of human inflammatory bowel disease, is characterized by primary immunodeficiencies. The nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) is essential for intestinal homeostasis in response to both dietary- and microbiota-derived signa...

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Detalhes bibliográficos
Main Authors: Peyrin-Biroulet, Laurent, Beisner, Julia, Wang, Guoxing, Nuding, Sabine, Oommen, Sajit Thottathil, Kelly, Denise, Parmentier-Decrucq, Erika, Dessein, Rodrigue, Merour, Emilie, Chavatte, Philipe, Grandjean, Teddy, Bressenot, Aude, Desreumaux, Pierre, Colombel, Jean-Frédéric, Desvergne, Béatrice, Stange, Eduard F., Wehkamp, Jan, Chamaillard, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889363/
https://ncbi.nlm.nih.gov/pubmed/20421464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905745107
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