Dichotomy in duration and severity of acute inflammatory responses in humans arising from differentially expressed proresolution pathways

Lipoxins (Lxs) and aspirin-triggered epi-Lxs (15-epi-LxA(4)) act through the ALX/FPRL1 receptor to block leukocyte trafficking, dampen cytokine/chemokine synthesis, and enhance phagocytic clearance of apoptotic leukocytes—key requisites for inflammatory resolution. Although studies using primarily i...

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Bibliografische gegevens
Hoofdauteurs: Morris, Thea, Stables, Melanie, Colville-Nash, Paul, Newson, Justine, Bellingan, Geoffrey, de Souza, Patricia M., Gilroy, Derek W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2010
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889345/
https://ncbi.nlm.nih.gov/pubmed/20421472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000373107
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