ACTH protects against glucocorticoid-induced osteonecrosis of bone

We report that adrenocorticotropic hormone (ACTH) protects against osteonecrosis of the femoral head induced by depot methylprednisolone acetate (depomedrol). This therapeutic response likely arises from enhanced osteoblastic support and the stimulation of VEGF by ACTH; the latter is largely respons...

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Detalhes bibliográficos
Main Authors: Zaidi, Mone, Sun, Li, Robinson, Lisa J., Tourkova, Irina L., Liu, Li, Wang, Yujuan, Zhu, Ling-Ling, Liu, Xuan, Li, Jianhua, Peng, Yuanzhen, Yang, Guozhe, Shi, Xingming, Levine, Alice, Iqbal, Jameel, Yaroslavskiy, Beatrice B., Isales, Carlos, Blair, Harry C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889316/
https://ncbi.nlm.nih.gov/pubmed/20421485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912176107
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