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Trans-synaptic EphB2–ephrin–B3 interaction regulates excitatory synapse density by inhibition of postsynaptic MAPK signaling

Nervous system function requires tight control over the number of synapses individual neurons receive, but the underlying cellular and molecular mechanisms that regulate synapse number remain obscure. Here we present evidence that a trans-synaptic interaction between EphB2 in the presynaptic compart...

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Main Authors: McClelland, Andrew C., Hruska, Martin, Coenen, Andrew J., Henkemeyer, Mark, Dalva, Matthew B.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889310/
https://ncbi.nlm.nih.gov/pubmed/20410461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910644107
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