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Accounting for Disease Model Uncertainty in Mapping Heterogeneous Traits – A Bayesian Model Averaging Approach
BACKGROUND: Locus heterogeneity, wherein a disease can be caused in different individuals by different genes and/or environmental factors, is a ubiquitous feature of complex traits. A Bayesian approach has been proposed to account for variable rates of heterogeneity across families in a parametric l...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
S. Karger AG
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2889260/ https://ncbi.nlm.nih.gov/pubmed/20339303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000298285 |
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