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Accounting for Disease Model Uncertainty in Mapping Heterogeneous Traits – A Bayesian Model Averaging Approach

BACKGROUND: Locus heterogeneity, wherein a disease can be caused in different individuals by different genes and/or environmental factors, is a ubiquitous feature of complex traits. A Bayesian approach has been proposed to account for variable rates of heterogeneity across families in a parametric l...

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Detalhes bibliográficos
Main Authors: Biswas, Swati, Papachristou, Charalampos
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889260/
https://ncbi.nlm.nih.gov/pubmed/20339303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000298285
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