Pro-2-PAM Therapy for Central and Peripheral Cholinesterases

Novel therapeutics to overcome the toxic effects of organophosphorus (OP) chemical agents are needed due to the documented use of OPs in warfare (e.g. 1980–1988 Iran/Iraq war) and terrorism (e.g. 1995 Tokyo subway attacks). Standard OP exposure therapy in the United States consists of atropine sulfa...

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Main Authors: DeMar, James C., Clarkson, Edward D., Ratcliffe, Ruthie H., Campbell, Amy J., Thangavelu, Sonia G., Herdman, Christine A., Leader, Haim, Schulz, Susan M., Marek, Elizabeth, Medynets, Marie A., Ku, Theresa C., Evans, Sarah A., Khan, Farhat A., Owens, Roberta R., Nambiar, Madhusoodana P., Gordon, Richard K.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889221/
https://ncbi.nlm.nih.gov/pubmed/20156430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2010.02.015
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