Human Prostate Fibroblasts Induce Growth and Confer Castration Resistance and Metastatic Potential in LNCaP Cells

BACKGROUND: The tumor microenvironment is important for progressive and metastatic disease. OBJECTIVE: To study the hypothesis that prostate fibroblasts have differential ability to induce castration-resistant prostate cancer (PCa) and metastatic progression and whether this effect might vary depend...

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Main Authors: Thalmann, George N., Rhee, Hong, Sikes, Robert A., Pathak, Sen, Multani, Ashi, Zhau, Haiyen E., Marshall, Fray F., Chung, Leland W.K.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889152/
https://ncbi.nlm.nih.gov/pubmed/19747763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2009.08.026
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