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Binding of complement component C3b to glycoprotein gC of herpes simplex virus type 1: mapping of gC-binding sites and demonstration of conserved C3b binding in low-passage clinical isolates.

The sites on glycoprotein gC of herpes simplex virus type 1 (HSV-1) which bind complement component C3b were evaluated by using anti-gC monoclonal antibodies and mutants which have alterations at defined regions of the glycoprotein. Monoclonal antibodies were incubated with HSV-1-infected cells in a...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Friedman, H M, Glorioso, J C, Cohen, G H, Hastings, J C, Harris, S L, Eisenberg, R J
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1986
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288914/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3021981/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.60.2.470-475.1986
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