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γ(c) deficiency precludes CD8(+) T cell memory despite formation of potent T cell effectors

Several cytokines (including IL-2, IL-7, IL-15, and IL-21) that signal through receptors sharing the common γ chain (γ(c)) are critical for the generation and peripheral homeostasis of naive and memory T cells. Recently, we demonstrated that effector functions fail to develop in CD4(+) T cells that...

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Hlavní autoři: Decaluwe, Hélène, Taillardet, Morgan, Corcuff, Erwan, Munitic, Ivana, Law, Helen K. W., Rocha, Benedita, Rivière, Yves, Di Santo, James P.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889085/
https://ncbi.nlm.nih.gov/pubmed/20439728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913729107
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