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Simulation of cell motility that reproduces the force–velocity relationship

Many cells crawl by extending an actin-rich pseudopod. We have devised a simulation that describes how the polymerization kinetics of a branched actin filament network, coupled with excluded volume effects, powers the motility of crawling cells such as amoebae and fish keratocytes. Our stochastic si...

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Hlavní autoři: Schreiber, Christian H., Stewart, Murray, Duke, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889078/
https://ncbi.nlm.nih.gov/pubmed/20439759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002538107
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