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Simulation of cell motility that reproduces the force–velocity relationship

Many cells crawl by extending an actin-rich pseudopod. We have devised a simulation that describes how the polymerization kinetics of a branched actin filament network, coupled with excluded volume effects, powers the motility of crawling cells such as amoebae and fish keratocytes. Our stochastic si...

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Bibliografiske detaljer
Main Authors: Schreiber, Christian H., Stewart, Murray, Duke, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889078/
https://ncbi.nlm.nih.gov/pubmed/20439759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002538107
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