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Common INSIG2 polymorphisms are associated with age-related changes in body size and HDL-cholesterol from young adulthood to middle-age

Insulin-induced gene 2 (INSIG2) plays an important role in the regulation of cholesterol and fatty acids synthesis. A polymorphism, rs7566605, located 10 kb upstream of the INSIG2 gene was identified in a genome-wide association study of obesity. We conducted an association study of 12 INSIG2 tagSNP...

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Bibliografiske detaljer
Main Authors: Fornage, Myriam, Papanicolaou, George, Lewis, Cora E., Boerwinkle, Eric, Siscovick, David S.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888786/
https://ncbi.nlm.nih.gov/pubmed/20045156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2009.11.005
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