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Secreted cysteine proteases of the carcinogenic liver fluke, Opisthorchis viverrini: regulation of cathepsin F activation by autocatalysis and trans-processing by cathepsin B

Opisthorchis viverrini is an important helminth pathogen of humans that is endemic in Thailand and Laos. Adult flukes reside within host bile ducts and feed on epithelial tissue and blood cells. Chronic opisthorchiasis is associated with severe hepatobiliary diseases such as cholangiocarcinoma. Here...

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Detalhes bibliográficos
Main Authors: Sripa, Jittiyawadee, Laha, Thewarach, To, Joyce, Brindley, Paul J., Sripa, Banchob, Kaewkes, Sasithorn, Dalton, John P., Robinson, Mark W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888773/
https://ncbi.nlm.nih.gov/pubmed/20070308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2010.01433.x
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