Paroxetine-Induced Increase in Activity of Locus Coeruleus Neurons in Adolescent Rats: Implication of a Countertherapeutic Effect of an Antidepressant

The concern that antidepressant (AD) drugs, especially selective serotonin reuptake inhibitors and paroxetine (PAR) in particular, can increase suicidality during the early treatment of juvenile patients (children and adolescents) has created a dilemma for clinicians treating depressives. Although p...

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Autori principali: West, Charles Hutchison Keesor, Ritchie, James Carl, Weiss, Jay Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888691/
https://ncbi.nlm.nih.gov/pubmed/20357759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.34
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