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Unfolding individual Als5p adhesion proteins on live cells

Elucidating the molecular mechanisms behind the strength and mechanics of cell adhesion proteins is of central importance in cell biology, and offers exciting avenues for the identification of potential drug targets. Here we use single-molecule force spectroscopy to investigate the adhesive and mech...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Alsteens, David, Dupres, Vincent, Klotz, Stephen A., Gaur, Nand K., Lipke, Peter N., Dufrêne, Yves F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888673/
https://ncbi.nlm.nih.gov/pubmed/19534503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn900078p
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