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Nanog Variability and Pluripotency Regulation of Embryonic Stem Cells - Insights from a Mathematical Model Analysis

The expression of the transcription factors Oct4, Sox2, and Nanog is commonly associated with pluripotency of mouse embryonic stem (ES) cells. However, recent observations suggest that ES cell populations are heterogeneous with respect to the expression of Nanog and that individual ES cells reversib...

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書目詳細資料
Main Authors: Glauche, Ingmar, Herberg, Maria, Roeder, Ingo
格式: Artigo
語言:Inglês
出版: Public Library of Science 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888652/
https://ncbi.nlm.nih.gov/pubmed/20574542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011238
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