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Expanded Polyfunctional T Cell Response to Mycobacterial Antigens in TB Disease and Contraction Post-Treatment

BACKGROUND: T cells producing multiple factors have been shown to be required for protection from disease progression in HIV but we have recently shown this not to be the case in TB. Subjects with active disease had a greater proportion of polyfunctional cells responding to ESAT-6/CFP-10 stimulation...

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Detalhes bibliográficos
Main Authors: Young, James M., Adetifa, Ifedayo M. O., Ota, Martin O. C., Sutherland, Jayne S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888639/
https://ncbi.nlm.nih.gov/pubmed/20574540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011237
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