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MicroRNA 128a Increases Intracellular ROS Level by Targeting Bmi-1 and Inhibits Medulloblastoma Cancer Cell Growth by Promoting Senescence

BACKGROUND: MicroRNAs (miRNAs) are a class of short non-coding RNAs that regulate cell homeostasis by inhibiting translation or degrading mRNA of target genes, and thereby can act as tumor suppressor genes or oncogenes. The role of microRNAs in medulloblastoma has only recently been addressed. We hy...

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Main Authors: Venkataraman, Sujatha, Alimova, Irina, Fan, Rong, Harris, Peter, Foreman, Nicholas, Vibhakar, Rajeev
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888574/
https://ncbi.nlm.nih.gov/pubmed/20574517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010748
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