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Posttranscriptional Regulation of Cyclooxygenase 2 Expression in Colorectal Cancer
Cyclooxygenase (COX)-2 enzyme catalyzes the rate-limiting step of prostaglandin formation in pathogenic states, and overexpression of COX-2 occurs at multiple stages of colon carcinogenesis, allowing elevated prostaglandin synthesis to occur in the tumor microenvironment. In normal cells, COX-2 expr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2888501/ https://ncbi.nlm.nih.gov/pubmed/20577575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11888-010-0044-3 |
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