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CRF(2) null mutation increases sensitivity to isolation rearing effects on locomotor activity in mice

BACKGROUND: Developmental stressors are consistently reported to increase risk for certain neuropsychiatric disorders including schizophrenia, depression, and post-traumatic stress disorder. Recent clinical evidence supports a “double-hit” hypothesis of genetic vulnerability interacting with develop...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gresack, Jodi, Powell, Susan, Geyer, Mark, Poore, Mary-Stenzel, Coste, Sarah, Risbrough, Victoria
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888500/
https://ncbi.nlm.nih.gov/pubmed/20466421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.npep.2010.04.005
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