Striatal Overexpression of ΔFosB Reproduces Chronic Levodopa-Induced Involuntary Movements

Long-term dopamine replacement therapy in Parkinson's disease leads to the development of disabling involuntary movements named dyskinesias that are related to adaptive changes in striatal signaling pathways. The chronic transcription factor ΔFosB, which is overexpressed in striatal neurons aft...

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Detalhes bibliográficos
Main Authors: Cao, Xuebing, Yasuda, Toru, Uthayathas, Subramaniam, Watts, Ray L., Mouradian, M. Maral, Mochizuki, Hideki, Papa, Stella M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888489/
https://ncbi.nlm.nih.gov/pubmed/20505100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0252-10.2010
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