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Identification of a Thiol/Disulfide Redox Switch in the Human BK Channel That Controls Its Affinity for Heme and CO

Heme is a required prosthetic group in many electron transfer proteins and redox enzymes. The human BK channel, which is a large-conductance Ca(2+) and voltage-activated K(+) channel, is involved in the hypoxic response in the carotid body. The BK channel has been shown to bind and undergo inhibitio...

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Bibliografiset tiedot
Päätekijät: Yi, Li, Morgan, Jeffrey T., Ragsdale, Stephen W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888424/
https://ncbi.nlm.nih.gov/pubmed/20427280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.116483
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