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Obligate Ordered Binding of Human Lactogenic Cytokines

Class 1 cytokines bind two receptors to create an active heterotrimeric complex. It has been argued that ligand binding to their receptors is an ordered process, but a structural mechanism describing this process has not been determined. We have previously described an obligate ordered binding mecha...

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Autori principali: Voorhees, Jeffery L., Brooks, Charles L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888414/
https://ncbi.nlm.nih.gov/pubmed/20427283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.084988
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