Protein Kinase Cθ Negatively Regulates Store-independent Ca(2+) Entry and Phosphatidylserine Exposure Downstream of Glycoprotein VI in Platelets

Platelet activation must be tightly controlled to provide an effective, but not excessive, response to vascular injury. Cytosolic calcium is a critical regulator of platelet function, including granule secretion, integrin activation, and phosphatidylserine (PS) exposure. Here we report that the nove...

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Bibliografiske detaljer
Main Authors: Harper, Matthew T., Poole, Alastair W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888397/
https://ncbi.nlm.nih.gov/pubmed/20388711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.085654
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