Cluster Intradermal DNA Vaccination Rapidly Induces E7-specific CD8(+) T Cell Immune Responses Leading to Therapeutic Antitumor Effects

Intradermal administration of DNA vaccines via a gene gun represents a feasible strategy to deliver DNA directly into the professional antigen-presenting cells (APCs) in the skin. This helps to facilitate the enhancement of DNA vaccine potency via strategies that modify the properties of APCs. We ha...

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Detalhes bibliográficos
Main Authors: Peng, Shiwen, Trimble, Cornelia, Alvarez, Ronald D., Huh, Warner K., Lin, Zhenhua, Monie, Archana, Hung, Chien-Fu, Wu, T.-C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888272/
https://ncbi.nlm.nih.gov/pubmed/18401437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2008.53
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