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Systemic vasculopathy with altered vasoreactivity in a transgenic mouse model of scleroderma

INTRODUCTION: Vasculopathy, including altered vasoreactivity and abnormal large vessel biomechanics, is a hallmark of systemic sclerosis (SSc). However, the pathogenic link with other aspects of the disease is less clear. To assess the potential role of transforming growth factor beta (TGF-β) overac...

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Detalhes bibliográficos
Main Authors: Derrett-Smith, Emma C, Dooley, Audrey, Khan, Korsa, Shi-wen, Xu, Abraham, David, Denton, Christopher P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888224/
https://ncbi.nlm.nih.gov/pubmed/20398328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2986
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