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The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial

INTRODUCTION: The purpose of this study was to compare urate-lowering (UL) efficacy and safety of daily febuxostat and allopurinol in subjects with gout and serum urate (sUA) ≥ 8.0 mg/dL in a six-month trial. METHODS: Subjects (n = 2,269) were randomized to febuxostat 40 mg or 80 mg, or allopurinol...

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Bibliografische gegevens
Hoofdauteurs: Becker, Michael A, Schumacher, H Ralph, Espinoza, Luis R, Wells, Alvin F, MacDonald, Patricia, Lloyd, Eric, Lademacher, Christopher
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888216/
https://ncbi.nlm.nih.gov/pubmed/20370912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2978
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