B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B-cell maturation antigen-immunoglobulin

INTRODUCTION: B-lymphocyte stimulator (BLyS) and a proliferation-inducing ligand (APRIL) are members of the tumor necrosis factor (TNF) family that regulate B-cell maturation, survival, and function. They are overexpressed in a variety of autoimmune diseases and reportedly exist in vivo not only as...

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Main Authors: Dillon, Stacey R, Harder, Brandon, Lewis, Kenneth B, Moore, Margaret D, Liu, Hong, Bukowski, Thomas R, Hamacher, Nels B, Lantry, Megan M, Maurer, Mark, Krejsa, Cecile M, Ellsworth, Jeff L, Pederson, Susan, Elkon, Keith B, Wener, Mark H, Dall'Era, Maria, Gross, Jane A
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2010
נושאים:
Research article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888197/
https://ncbi.nlm.nih.gov/pubmed/20302641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2959
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