Circulating surfactant protein -D is low and correlates negatively with systemic inflammation in early, untreated rheumatoid arthritis

INTRODUCTION: Surfactant protein D (SP-D) is a collectin with immuno-regulatory functions, which may depend on oligomerization. Anti-microbial and anti-inflammatory properties have been attributed to multimeric SP-D variants, while trimeric subunits per se have been suggested to enhance inflammation...

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Główni autorzy: Christensen, Anne Friesgaard, Sørensen, Grith Lykke, Hørslev-Petersen, Kim, Holmskov, Uffe, Lindegaard, Hanne Merete, Junker, Kirsten, Hetland, Merete Lund, Stengaard-Pedersen, Kristian, Jacobsen, Søren, Lottenburger, Tine, Ellingsen, Torkell, Andersen, Lis Smedegaard, Hansen, Ib, Skjødt, Henrik, Pedersen, Jens Kristian, Lauridsen, Ulrik Birk, Svendsen, Anders, Tarp, Ulrik, Pødenphant, Jan, Vestergaard, Aage, Jurik, Anne Grethe, Østergaard, Mikkel, Junker, Peter
Format: Artigo
Język:Inglês
Wydane: BioMed Central 2010
Hasła przedmiotowe:
Research article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888186/
https://ncbi.nlm.nih.gov/pubmed/20211020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2948
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