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A Formal [4+4] Complementary Ambiphile Pairing (CAP) Reaction: A New Cyclization Pathway for ortho-Quinone Methides

[Image: see text] A formal, one-pot, [4+4] cyclization pathway for the generation of 8-member sultams via in-situ generation of an ortho-quinone methide (o-QM) is reported. The pairing of ambiphilic synthons in a complementary fashion is examined whereby o-fluorobenzenesulfonamides are merged with i...

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Detalhes bibliográficos
Main Authors: Samarakoon, Thiwanka B., Hur, Moon Y., Kurtz, Ryan D., Hanson, Paul. R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888001/
https://ncbi.nlm.nih.gov/pubmed/20394415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol100495w
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