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Reagent based DOS: A “Click, Click, Cyclize” strategy to probe chemical space

The synthesis of small organic molecules as probes for discovering new therapeutic agents has been an important aspect of chemical-biology. Herein we report a reagent-based, diversity-oriented synthetic (DOS) strategy to probe chemical and biological space via a “Click, Click, Cyclize” protocol. In...

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Main Authors: Rolfe, Alan, Lushington, Gerald. H., Hanson, Paul. R.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888000/
https://ncbi.nlm.nih.gov/pubmed/20401396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b927161a
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