Exercise intensity-dependent regulation of peroxisome proliferator-activated receptor γ coactivator-1α mRNA abundance is associated with differential activation of upstream signalling kinases in human skeletal muscle

Skeletal muscle contraction increases intracellular ATP turnover, calcium flux, and mechanical stress, initiating signal transduction pathways that modulate peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α)-dependent transcriptional programmes. The purpose of this study was to det...

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Main Authors: Egan, Brendan, Carson, Brian P, Garcia-Roves, Pablo M, Chibalin, Alexander V, Sarsfield, Fiona M, Barron, Niall, McCaffrey, Noel, Moyna, Niall M, Zierath, Juleen R, O’Gorman, Donal J
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2010
主題:
Skeletal Muscle and Exercise
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887994/
https://ncbi.nlm.nih.gov/pubmed/20308248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.188011
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