Exercise intensity-dependent regulation of peroxisome proliferator-activated receptor γ coactivator-1α mRNA abundance is associated with differential activation of upstream signalling kinases in human skeletal muscle

Skeletal muscle contraction increases intracellular ATP turnover, calcium flux, and mechanical stress, initiating signal transduction pathways that modulate peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α)-dependent transcriptional programmes. The purpose of this study was to det...

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Detalhes bibliográficos
Main Authors: Egan, Brendan, Carson, Brian P, Garcia-Roves, Pablo M, Chibalin, Alexander V, Sarsfield, Fiona M, Barron, Niall, McCaffrey, Noel, Moyna, Niall M, Zierath, Juleen R, O’Gorman, Donal J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Skeletal Muscle and Exercise
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887994/
https://ncbi.nlm.nih.gov/pubmed/20308248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.188011
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