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Adenovirus helper function for growth of adeno-associated virus: effect of temperature-sensitive mutations in adenovirus early gene region 2.

Adeno-associated virus (AAV) grows efficiently only in cells that are also infected with an adenovirus (Ad). We employed Ad mutants to determine which genes may be required for the AAV helper function. Two mutants of Ad type 5 (Ad5), Ad5ts125 and Ad5ts107, with temperature-sensitive lesions in the E...

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Autores principales: Myers, M W, Laughlin, C A, Jay, F T, Carter, B J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1980
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC288783/
https://ncbi.nlm.nih.gov/pubmed/6251278
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